G6pd list of foods and drugs to avoid pdf
G6PD deficiencyG6PD deficiency is a genetic abnormality that results in an inadequate amount of glucosephosphate dehydrogenase G6PD in the blood. This is a very important enzyme or protein that regulates various biochemical reactions in the body. G6PD is also responsible for keeping red blood cells healthy so they can function properly and live a normal life span. Without enough of it, red blood cells break down prematurely. This early destruction of red blood cells is known as hemolysis , and it can eventually lead to hemolytic anemia.
Pharmacology: Drugs causing hemolysis in G6PD deficiency
Fortunately, most people with G6PD deficiency do not have problems on a daily basis. However, there are certain medications or foods that increase the rate of red blood cell breakdown. Antibiotics referred to as "sulfa" drugs should be avoided. These antibiotics are typically used to treat skin or urinary tract bladder infections. The two most common antibiotics in this group are Cipro ciprofloxacin and Levaquin levofloxacin. These antibiotics are commonly used in adults to treat urinary tract infections and pneumonia. Other antibiotics that should be avoided include nitrofurantoin and dapsone.
Glucosephosphate dehydrogenase G6PD is a substance that helps the body use sugar for energy. It is an enzyme, which means it speeds up chemical changes when the body converts sugar to energy. These are the cells that contain hemoglobin and carry oxygen throughout the body. The G6PD enzyme protects the red blood cells from harmful chemicals or toxins, which can build up in your body during certain illnesses or after taking some medicines. Normally, there are only tiny amounts of toxins in the body, and so it is not usually a problem for the G6PD enzyme to make them harmless. If G6PD is not present, strong chemical products are not neutralized and they can damage the hemoglobin inside red blood cells. A build-up of toxins or chemicals can cause the red blood cells to break apart and be destroyed also known as hemolysis.
Although most individuals are asymptomatic, it can lead to acute haemolytic anaemia with malaise, neonatal jaundice and haemoglobinuria in the presence of oxidative triggers. In our study, we also noted that there was no synthesized evidence on the roles of food and chemicals these individuals. We considered all study designs as long as they reported clinical outcomes along with indicators of haemolysis. Only 38 articles, describing 14 different types of food or chemical, were found a full list of the articles retrieved can be obtained by contacting S. This food additive has subsequently been banned in many countries, which may account for the paucity of report on it in recent years. Nevertheless, we urge caution while consuming any food which contains a high concentration of this agent in view of the potential for haemolysis and toxicity 7.
G6PD is important in protecting red blood cells.
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